Open AccessEvaluation of HER2/neu oncoprotein in serum & tissue samples of women with breast cancer
Author(s) -
Shailaja Shukla,
Bhawana Singh,
Om Prakash Pathania,
Manjula Jain
Publication year - 2016
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/0971-5916.191769
Subject(s) - her2/neu , immunohistochemistry , breast cancer , medicine , lymph node , pathology , biopsy , cancer , stage (stratigraphy) , oncogene , biology , paleontology , cell cycle
The proto-oncogene HER2/neu has been extensively studied in breast cancer patients. Serum levels of HER2/neu by ELISA in breast cancer patients were compared with tissue HER2/neu expression and with other clinicopathological parameters with the aim to investigate whether the serum assay could replace the established tests (IHC/FISH) for HER-2 status.