Open AccessPerioperative time course of matrix metalloproteinase-9 (MMP-9), its tissue inhibitor TIMP-1 & S100B protein in carotid surgery
Author(s) -
Bálint Nagy,
Gábor Woth,
Ákos Mérei,
L Nagy,
János Lantos,
Gábor Menyhei,
Lajos Bogár,
Diána Mühl
Publication year - 2016
Publication title -
indian journal of medical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.578
H-Index - 87
ISSN - 0971-5916
DOI - 10.4103/0971-5916.180212
Subject(s) - carotid endarterectomy , perioperative , medicine , matrix metalloproteinase , morning , inflammation , stroke (engine) , gastroenterology , surgery , anesthesia , carotid arteries , mechanical engineering , engineering
Ischaemic stroke is a life burdening disease for which carotid endarterectomy (CEA) is considered a gold standard intervention. Pro-inflammatory markers like matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) and S-100 Beta (S100B) may have a role in the early inflammation and cognitive decline following CEA. This study was aimed to describe the perioperative time courses and correlations between of MMP-9, TIMP-1 and S100B following CEA.