Open AccessAngiosarcoma of the scalp associated with Xeroderma pigmentosum
Author(s) -
Shilpi Sharma,
Anuja Deshmukh,
Munita Bal,
Devendra A Chaukar,
Anil D’Cruz
Publication year - 2012
Publication title -
indian journal of medical and paediatric oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.229
H-Index - 22
eISSN - 0975-2129
pISSN - 0971-5851
DOI - 10.4103/0971-5851.99753
Subject(s) - xeroderma pigmentosum , medicine , angiosarcoma , basal cell carcinoma , scalp , genodermatosis , occiput , dermatology , basal cell , pathology , dna , dna repair , genetics , surgery , biology , gene
Xeroderma pigmentosum (XP) is a rare autosomal recessive genodermatosis associated with hypersensitivity to ultraviolet light due to defects in Deoxyribonucleic acid (DNA) repair. These patients have more than a 1000-fold increased risk of developing skin cancers. Although multiple cutaneous malignancies are common, the simultaneous occurrence of angiosarcoma and basal cell carcinoma is a rare phenomenon. We report a case of a 25-year-old male with XP with angiosarcoma scalp and basal cell carcinoma of face and occiput and discuss the treatment of this aggressive neoplasm with a review of the literature pertaining to it.