Open AccessUlcerative colitis after renal transplantation: A case report and review of literature
Author(s) -
Sreejith Parameswaran,
Kartar Singh,
Ritambhra Nada,
Manish Rathi,
Harbir Singh Kohli,
Vivekanand Jha,
Krishan Lal Gupta,
Vinay Sakhuja
Publication year - 2011
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.78063
Subject(s) - medicine , calcineurin , ulcerative colitis , etiology , inflammatory bowel disease , transplantation , diarrhea , kidney transplantation , tacrolimus , disease , immunosuppression , immunology , intensive care medicine
Diarrhea is common after kidney transplantation and is usually related to immunosuppressive medication or is infective in etiology. Inflammatory bowel disease (IBD) is rare after kidney transplantation and is unexpected because the patient is already immunosuppressed. Specific immunomodulatory actions of calcineurin inhibitors have been hypothesized to play a role in the development of IBD in such patients. We report a case of IBD developing de novo after kidney transplantation. Our case is unique in that the patient was not on calcineurin inhibitors for 8 years prior to the development of IBD.