Open AccessDe Novo collapsing glomerulopathy in renal allograft in association with BK virus nephropathy in a child and stabilization of renal function by elimination of viremia
Author(s) -
DN Gera,
M. Shah,
VA Ghodela,
VivekB Kute,
HL Trivedi
Publication year - 2017
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.200516
Subject(s) - medicine , viremia , glomerulopathy , bk virus , renal biopsy , proteinuria , nephropathy , parvovirus , cytomegalovirus , immunology , renal function , virus , virology , kidney , kidney transplantation , viral disease , herpesviridae , endocrinology , diabetes mellitus
Well-recognized association between HIV 1 infection and collapsing glomerulopathy (CG) raises the possibility that intrarenal infection by other viruses may also contribute to the development of this lesion in native or post-transplant kidneys. There is evidence in literature about association of these lesions with cytomegalovirus, Epstein-Barr virus, hepatitis C virus, and parvovirus B19 infections. Here, we present a case report of post-transplant BK virus nephropathy in a male child who was found to have CG in subsequent biopsy 2 months later. His renal function and proteinuria were stabilized on elimination of viremia.