Open AccessAcyclovir-induced thrombotic microangiopathy
Author(s) -
Rahim Goli,
K K Mukku,
Sree Bhushan Raju Devaraju,
Megha S Uppin
Publication year - 2017
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.181453
Subject(s) - thrombotic microangiopathy , medicine , acute kidney injury , microangiopathy , interstitial nephritis , renal function , nephritis , gastroenterology , kidney , diabetes mellitus , endocrinology , disease
Acyclovir is a commonly used antiviral drug. Acute kidney injury (AKI) due to intratubular crystal precipitation and interstitial nephritis is well known. Here we present a case of acyclovir induced AKI in a 61 year old male with herpes zoster, which presented like thrombotic microangiopathy with acute interstitial nephritis. This is the first case report on acyclovir causing thrombotic microaniopathy with partial improvement in renal function after plasmapharesis.