Open AccessSepticemic melioidosis in a transplant recipient causing graft dysfunction
Author(s) -
Subrahmanian Sathiavageesan
Publication year - 2016
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.168142
Subject(s) - melioidosis , burkholderia pseudomallei , medicine , immunosuppression , intensive care medicine , infectious disease (medical specialty) , immunology , transplantation , disease , indian subcontinent , pathology , bacteria , history , ancient history , genetics , biology
Melioidosis, an infectious disease caused by Burkholderia pseudomallei , is endemic in the Northern Australia and South-East Asia. It is an emerging disease in the Indian subcontinent. Melioidosis tends to run a potentially lethal course in immunocompromised individuals and data in renal transplantation are scarce. The clinical presentation of melioidosis is diverse, mimicking several other infectious diseases. Diagnosis could be delayed in transplant recipients. Choice and duration of antimicrobial therapy, management of immunosuppression, and patient and graft outcomes are other issues to be addressed. We report septicemic melioidosis with pulmonary involvement in a 32-year old renal transplant recipient that caused acute allograft dysfunction.