Open AccessCytomegalovirus infection inducing flare of Behcet's disease with possible recurrence of glomerulonephritis after renal transplantation
Author(s) -
RA Annigeri,
Murlidhar Rajagopalan,
Rama Mani,
SS Kaveripattu
Publication year - 2016
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.157418
Subject(s) - medicine , behcet's disease , cytomegalovirus , transplantation , cytomegalovirus infection , flare , membranoproliferative glomerulonephritis , disease , mesangial proliferative glomerulonephritis , glomerulonephritis , pathology , immunology , kidney , human cytomegalovirus , virus , herpesviridae , viral disease , physics , astrophysics
We present a case of young male with end-stage renal disease due to type III membranoproliferative glomerulonephritis (GN) and clinical features consistent with Behcet's disease (BD). He developed flare of BD 3 months after deceased donor renal transplantation following cytomegalovirus infection, in the form of oral and genital ulcers. He also had GN characterized by mild mesangial proliferation, neutrophilic infiltration and subepithelial, mesangial and intramembranous electron dense deposits, which could possibly be attributed to recurrence of renal disease due to BD. The clinical flare of BD was treated with colchicine with good response.