Open AccessGrave′s disease associated with immunoglobulin A nephropathy: A rare association
Author(s) -
Imran Ali Khan,
RA Bhat,
Iqra Hameed
Publication year - 2015
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.147373
Subject(s) - medicine , nephropathy , proteinuria , nephrotic syndrome , renal biopsy , glomerulonephritis , disease , gastroenterology , antibody , immunology , dermatology , biopsy , endocrinology , kidney , diabetes mellitus
Immunoglobulin A (Ig A) nephropathy is the most common form of primary glomerulonephritis. The association of Ig A nephropathy with Grave's disease has not been reported so far. We report a case of 20-year-old female with Grave's disease who presented with edema, facial puffiness, and decreased urine output. She was found to be hypertensive with renal failure and nephrotic range proteinuria. Renal biopsy revealed features of Ig A nephropathy. The patient was treated with oral corticosteroids (1 mg/kg/day). To our knowledge, this is the first case showing association of Grave's disease with Ig A nephropathy.