Open AccessTenofovir induced Fanconi syndrome: A rare cause of hypokalemic paralysis
Author(s) -
EP Venkatesan,
M B Pranesh,
G Gnanashanmugam,
J Balasubramaniam
Publication year - 2014
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.127898
Subject(s) - medicine , hypophosphatemia , fanconi syndrome , tenofovir , pediatrics , complication , proteinuria , paralysis , hypokalemic periodic paralysis , surgery , human immunodeficiency virus (hiv) , virology , kidney
We report a 55-year-old female who presented to the emergency department with acute onset quadriparesis. She was diagnosed to have acquired immunodeficiency syndrome 7 years ago and was on tenofovir based anti-retroviral therapy for past 10 months. As the patient also had hypophosphatemia, glucosuria and proteinuria Fanconi syndrome (FS) was suspected. She improved dramatically over next 12 h to regain normal power and also her renal functions improved over next few days. Tenofovir induced FS presenting as hypokalemic paralysis is very rare complication and is the first case reported from India.