Open AccessIgG4 related interstitial nephritis: A case report and review of literature
Author(s) -
Natarajan Gopalakrishnan,
Anitha Abraham,
T Balasubramaniyan,
Thanigachalam Dineshkumar,
J Dhanapriya,
N Malathy,
M Haris,
ND Srinivasa Prasad
Publication year - 2013
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.114489
Subject(s) - medicine , hepatosplenomegaly , pathology , interstitial nephritis , nephritis , proteinuria , fibrosis , retroperitoneal fibrosis , immunohistochemistry , kidney , disease
IgG4 interstitial nephritis is a recently described entity. A middle-aged gentleman with bilateral parotid enlargement, hepatosplenomegaly and generalized lymphadenopathy was referred to us for evaluation of renal failure. He had trace proteinuria and large kidneys. Kidney biopsy revealed interstitial nephritis with characteristic storiform fibrosis. Immunohistochemistry demonstrated intense staining for IgG4-secreting plasma cells in the interstitium.