Open AccessGelatin-thrombin hemostatic matrix injection to salvage refractory post-renal graft biopsy bleed
Author(s) -
Alok Jain,
Arobinda Gupta,
Anil Gulia,
Manoj Singhal,
Sanjeev Gulati,
Tiwari Sc,
Anant Kumar
Publication year - 2013
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.109447
Subject(s) - medicine , bleed , refractory (planetary science) , surgery , hemostatics , biopsy , nephrectomy , renal biopsy , thrombin , hemostasis , radiology , kidney , platelet , physics , astrobiology
Post-renal biopsy bleeding refractory to angioembolization usually requires graft nephrectomy as a life-saving measure. Gelatin-thrombin hemostatic matrix injection in the needle tract is a novel attempt to control bleeding in such cases and to salvage the allograft. We hereby describe two cases of post-graft biopsy bleed. Both these patients continued to bleed even after angioembolization. They were shifted to the operating room upon developing hypotension, having received multiple blood transfusions with the intention of performing graft nephrectomy to save their lives. However, bleeding was successfully controlled by using Gelatin-thrombin hemostatic matrix injection in the biopsy needle tract. Patients improved hemodynamically after the procedure. Graft function returned to normal in both the cases. At an average follow-up of 10.4 months, both the patients have shown stable graft functions.