Open AccessHepatitis C as a potential cause of IgA nephropathy
Author(s) -
Ak K. Dey,
A. Bhattacharya,
Arghya Majumdar
Publication year - 2013
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.109443
Subject(s) - medicine , proteinuria , nephropathy , ribavirin , oliguria , hepatitis c , gastroenterology , hepatitis , glomerulonephritis , anasarca , pegylated interferon , hepatitis c virus , immunology , kidney , virus , endocrinology , renal function , diabetes mellitus
This is a case report of a 16-year-old boy presenting with a history of oliguria and anasarca. Workup revealed marked proteinuria to the tune of 8 g/day. He was subsequently found to be hepatitis C positive. Genotype was hepatitis C virus type 6. Renal biopsy revealed mesangioproliferative glomerulonephritis with IgA deposits consistent with IgA nephropathy (IgAN). Initiation of oral ribavirin and pegylated interferon caused a marked reduction in proteinuria after 8 weeks of treatment. It was postulated that hepatitis C manifested as IgAN. This case report thus sheds light on the possibility of an association between hepatitis C and IgAN.