Open AccessCerebral infarction in patient with minimal change nephrotic syndrome
Author(s) -
Adarsh Babu,
Preetham Boddana,
Simon C. Robson,
Linmarie Ludeman
Publication year - 2013
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.107203
Subject(s) - medicine , nephrotic syndrome , proteinuria , minimal change disease , cerebral infarction , magnetic resonance imaging , renal biopsy , cerebral edema , cardiology , thrombosis , radiology , pathology , biopsy , ischemia , kidney , focal segmental glomerulosclerosis
We report a case of 68-year-old Caucasian man who presented with cerebral infarcts secondary to arterial thrombosis associated with nephrotic syndrome. His initial presentation included edema of legs, left hemiparesis, and right-sided cerebellar signs. Investigations with computed tomography and magnetic resonance imaging of brain showed multiple cerebral infarcts in middle cerebral and posterior cerebral artery territory. Blood and urine investigations also showed impaired renal function, hypercholesterolemia, hypoalbuminaemia, and nephrotic range proteinuria. Renal biopsy showed minimal change disease. Cerebral infarcts were treated with antiplatelet agents and nephrotic syndrome was treated with high dose steroids. Patient responded well to the treatment and is all well till date.