Open AccessReversible acute kidney injury due to bilateral papillary necrosis in a patient with leptospirosis and diabetes mellitus
Author(s) -
P S Subrahmanian,
Georgi Abraham,
K Thirumurthi,
Milly Mathew,
Yuvaram N.V. Reddy
Publication year - 2012
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.103927
Subject(s) - medicine , leptospirosis , acute tubular necrosis , ceftriaxone , diabetes mellitus , acute kidney injury , leptospira , hemodialysis , renal biopsy , dialysis , necrosis , interstitial nephritis , kidney , surgery , gastroenterology , pathology , antibiotics , endocrinology , microbiology and biotechnology , biology
A 60-year-old lady with type 2 diabetes mellitus and hypertension was referred for fever, bilateral loin pain, and renal failure. Investigations showed severe acute renal failure, bilateral renal papillary necrosis (RPN), urinary tract infection (E. coli), and infection with leptospirosis: Leptospira icterohemorrhagica; serovar hardjo. Renal biopsy showed tubulointerstitial nephritis with mesangial proliferation. The diagnosis was bilateral RPN in a diabetic lady with acute renal failure due to leptospirosis. The patient was successfully treated with hemodialysis, injection ceftriaxone, and benzyl penicillin.