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Objectives : To evaluate the coronary arteries by CT angiography (CTA) and calcium scoring (CS) with 16-slice MDCT for detection of coronary artery disease (CAD) by plaque detection, plaque characterization as well as quantifying luminal narrowing and to correlate the incidence and severity of CAD in diabetic and nondiabetic subjects.  Materials and Methods:  One hundred and five patients (76 men, 29 women) aged 26-89 years underwent MDCT angiography with CS. Significant luminal stenosis was defined as a reduction in lumen diameter greater than or equal to 50%. The presence of calcification was determined by using the Agatston method. Incidence and severity of CAD were noted in diabetic (DM) and nondiabetic (nonDM) patients.  Results : On comparing the CS in patients with DM and nonDM, there was a marked increase in the CS in diabetic patients. Seventy six per cent of diabetic patients showed calcific plaques whereas only 37% of nonDM patients showed calcific plaques.  Conclusion:  DM patients show significantly more CS than nonDM patients. Calcific plaques are more common in DM than nonDM patients. Double and triple vessel involvement is more common in DM than the nonDM patients.

indian journal of radiology and imaging - new series/indian journal of radiology and imaging/indian journal of radiology and imaging

Evaluation of coronary artery disease by computed tomography angiography and calcium scoring on a 16-slice MDCT scanner in diabetic and nondiabetic patients