Open AccessA rare case of extra nodal Rosai-Dorfman disease with isolated multifocal osseous manifestation
Author(s) -
Maharshi H Patel,
Kedar Jambhekar,
Tarun Pandey,
Roopa Ram
Publication year - 2015
Publication title -
indian journal of radiology and imaging - new series/indian journal of radiology and imaging/indian journal of radiology and imaging
Language(s) - English
Resource type - Journals
eISSN - 0971-3026
pISSN - 0970-2016
DOI - 10.4103/0971-3026.161459
Subject(s) - rosai–dorfman disease , medicine , sinus histiocytosis with massive lymphadenopathy , cervical lymphadenopathy , disease , histiocytosis , pathology , sinus (botany) , dermatology , botany , biology , genus
Sinus histiocytosis with massive lymphadenopathy (SHML) or Rosai-Dorfman disease is a non-neoplastic condition which typically presents as massive, bilateral cervical lymphadenopathy and can involve multiple extranodal organ systems such as skin, eyes, and upper respiratory tract in about 28% cases. Bone lesions in association with nodal disease are seen in less than 10% cases. Isolated bone involvement as the only manifestation of SHML is extremely rare, with less than 50 cases reported in the literature. We report a very uncommon case of Rosai-Dorfman disease with isolated multifocal osseous involvement as the only presenting feature, involving about 10 different sites with no lymphadenopathy or other organ system involvement.