Open AccessImaging for assessment of treatment response in hepatocellular carcinoma: Current update
Author(s) -
Koichi Hayano,
Sang Ho Lee,
Dushyant V. Sahani
Publication year - 2015
Publication title -
indian journal of radiology and imaging - new series/indian journal of radiology and imaging/indian journal of radiology and imaging
Language(s) - English
Resource type - Journals
eISSN - 0971-3026
pISSN - 0970-2016
DOI - 10.4103/0971-3026.155835
Subject(s) - medicine , hepatocellular carcinoma , response evaluation criteria in solid tumors , radiology , medical physics , oncology , pathology , clinical trial , phases of clinical research
Morphologic methods such as the Response Evaluation Criteria in Solid Tumors (RECIST) are considered as the gold standard for response assessment in the management of cancer. However, with the increasing clinical use of antineoplastic cytostatic agents and locoregional interventional therapies in hepatocellular carcinoma (HCC), conventional morphologic methods are confronting limitations in response assessment. Thus, there is an increasing interest in new imaging methods for response assessment, which can evaluate tumor biology such as vascular physiology, fibrosis, necrosis, and metabolism. In this review, we discuss various novel imaging methods for response assessment and compare them with the conventional ones in HCC.