Open AccessRole of dexmedetomidine in early extubation of the intensive care unit patients
Author(s) -
Shikha Gupta,
Dupinder Singh,
Dinesh Sood,
Suneet Kathuria
Publication year - 2015
Publication title -
journal of anaesthesiology-clinical pharmacology/journal of anaesthesiology clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.466
H-Index - 32
eISSN - 2231-2730
pISSN - 0970-9185
DOI - 10.4103/0970-9185.150554
Subject(s) - dexmedetomidine , midazolam , medicine , sedation , anesthesia , mechanical ventilation , intensive care unit , sedative , heart rate , intubation , ventilation (architecture) , weaning , hemodynamics , blood pressure , intensive care medicine , mechanical engineering , engineering
Patients on ventilatory support in intensive care unit (ICU) require sedation and analgesia to facilitate mechanical ventilation and endotracheal tube tolerance. The selection of the agent should be such that it does not interfere with the early extubation of the patients. We compared the efficacy of dexmedetomidine with midazolam to facilitate extubation of patients from mechanical ventilation in terms of the sedative properties, cardiovascular responses, ventilation, and extubation characteristics and safety profile.