Open AccessBetahistine as an add-on: The magic bullet for postoperative nausea, vomiting and dizziness after middle ear surgery?
Author(s) -
Sandip Mukhopadhyay,
Mausumi Niyogi,
Ritam Ray,
Basabdatta Samanta Mukhopadhyay,
Manotosh Dutta,
Monoj Mukherjee
Publication year - 2013
Publication title -
journal of anaesthesiology-clinical pharmacology/journal of anaesthesiology clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.466
H-Index - 32
eISSN - 2231-2730
pISSN - 0970-9185
DOI - 10.4103/0970-9185.111725
Subject(s) - medicine , ondansetron , betahistine , anesthesia , vomiting , nausea , placebo , vertigo , postoperative nausea and vomiting , surgery , alternative medicine , pathology
Patients undergoing middle ear surgery experience variable degrees of postoperative nausea and vomiting (PONV) despite prophylaxis and treatment with ondansetron or other 5HT3 receptor antagonists. Furthermore vertigo or dizziness are not well controlled perioperatively. Role of betahistine was tested as an add-on to ondansetron in control of PONV and vertigo in middle ear surgery cases.