Open AccessAdenocarcinoma of the lung with positive epidermal growth factor receptor mutation in pregnancy
Author(s) -
Gina Amanda,
Agus Dwi Susanto,
Dicky Soehardiman,
Dianiati Kusumo Sutoyo,
Yuyun Lisnawati,
Boy Busmar,
Andika Chandra Putra,
Erlang Samoedro,
Elisna Syahruddin
Publication year - 2017
Publication title -
lung india
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 25
eISSN - 0974-598X
pISSN - 0970-2113
DOI - 10.4103/0970-2113.217574
Subject(s) - medicine , pleural effusion , pregnancy , chest radiograph , adenocarcinoma , epidermal growth factor receptor , lung , gestation , radiology , adenocarcinoma of the lung , biopsy , thorax (insect anatomy) , cancer , genetics , anatomy , biology
Lung cancer during pregnancy is a rare condition. We report a case of 28-year-old nonsmoker female, who was admitted to our hospital with massive left pleural effusion in the 21st week of gestation. Chest radiograph showed total left hemithorax opacity with contralateral mediastinal deviation. Pleural biopsy and cytological examination of pleural fluid revealed adenocarcinoma invasion with positive epidermal growth factor receptor mutation status. Cesarean section was performed at 32 weeks of pregnancy, and targeted therapy was given to this patient after delivery. Computed tomography of the thorax showed a mass lesion in the left hemithorax with liver metastases. Unfortunately, the patient died 10 days after delivery.