Open AccessAnalysis of HLA association among North Indian HIV-positive individuals co-infected with Mycobacterium tuberculosis
Author(s) -
Biman Saikia,
Ajay Wanchu,
Sobhana Mahakur,
Mahendra Bind,
Krishnakali Sarkar,
Ranjana Walker Minz
Publication year - 2015
Publication title -
lung india
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 25
eISSN - 0974-598X
pISSN - 0970-2113
DOI - 10.4103/0970-2113.164166
Subject(s) - medicine , tuberculosis , human leukocyte antigen , mycobacterium tuberculosis , immunology , human immunodeficiency virus (hiv) , disease , immune system , antigen , pathology
Genetic variation in HLA genes influence the immune response and may thus contribute to differential development of tuberculosis (TB) in HIV-infected individuals. The study was designed to determine whether HLA polymorphisms influence the development of Mycobacterium tuberculosis infection in HIV-infected individuals.