Open AccessRole of doxycycline to resolve different types of non-malignant lung and pleural pathology: The results of a pilot observation
Author(s) -
Parthasarathi Bhattacharyya,
Rana Dey,
Debasri Saha,
Nag S,
Sudipta Ghosh,
Sushmita Roy Chowdhury,
Dhiman Ganguly
Publication year - 2015
Publication title -
lung india
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 25
eISSN - 0974-598X
pISSN - 0970-2113
DOI - 10.4103/0970-2113.148447
Subject(s) - medicine , doxycycline , malignancy , visual analogue scale , matrix metalloproteinase , adenocarcinoma , pulmonologists , lung , pathology , prospective cohort study , radiology , surgery , cancer , antibiotics , intensive care medicine , microbiology and biotechnology , biology
Lung lesions may develop from tissue reactions to known or unknown stimuli and present with different morphological descriptions. The pathogenesis may be induced and maintained by different bioactive substances, of which, the upregulation matrix metalloproteinases (MMPs) play a vital role. Inhibition of the MMPs, therefore, may be a prospective mode of therapy for such lesions.