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Pleuro-peritoneal lymphomatosis with concurrent tonsillar involvement in T-cell nonHodgkin′s lymphoma: Clinical presentation mimicking disseminated tuberculosis
Author(s) -
Punit Tiwari,
Karan Madan,
Deepali Jain,
Rakesh Kumar,
Anant Mohan,
Randeep Guleria
Publication year - 2014
Publication title -
lung india
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 25
eISSN - 0974-598X
pISSN - 0970-2113
DOI - 10.4103/0970-2113.142125
Subject(s) - medicine , lymphoma , tonsil , adenosine deaminase , pleural effusion , tuberculosis , pathology , biopsy , fever of unknown origin , dermatology , adenosine
A young male patient had been evaluated for pleural effusion at another center wherein on the basis of exudative, lymphocyte predominant pleural effusion with high pleural fluid adenosine deaminase (ADA) levels and tuberculin skin test (TST) reactivity, antituberculous medications had been administered. Reevaluation in view of worsening symptoms led to confirmation of the diagnosis of T-cell lymphoblastic lymphoma with pleuro-peritoneal lymphomatosis and tonsillar involvement. This case highlights the fact that elevated ADA levels should not be taken as surrogate for a diagnosis of TB in the absence of histopathological/microbiological confirmation even in countries with high tuberculosis (TB) prevalence. Tonsil in an uncommon site of involvement in patients with T-cell lymphoma. As the diagnosis in our patient was confirmed from biopsy of a tonsillar mass, a thorough physical examination should be performed in all patients with a suspected diagnosis of lymphoma.

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