Open AccessNon-resolving pneumonia: A rare presentation of progressive disseminated histoplasmosis
Author(s) -
Supriya Sarkar,
Sushmita Kaushik,
Arnab Kumar Maji,
Anjan Kundu
Publication year - 2014
Publication title -
lung india
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 25
eISSN - 0974-598X
pISSN - 0970-2113
DOI - 10.4103/0970-2113.125993
Subject(s) - histoplasmosis , medicine , histoplasma , hepatosplenomegaly , histoplasma capsulatum , pleural effusion , bronchoalveolar lavage , dermatology , pathology , mediastinal lymphadenopathy , pneumonia , tuberculosis , biopsy , disease , radiology , lung
Histoplasmosis, a fungal disease caused by Histoplasma capsulatum, is endemic in North and South America. Except few scattered cases, the disease is considered to be a non-entity in India. Furthermore, disseminated histoplasmosis is rare in the immunocompetent individuals. We report an adolescent boy presenting as middle lobe consolidation which did not respond to antibiotics. His condition deteriorated with the development of mediastinal lymphadenopathy, pleural effusion and hepatosplenomegaly. A diagnosis of progressive disseminated histoplasmosis was established by his clinical findings as well as bronchoscopic biopsy, transbronchial needle aspiration cytology and bronchoalveolar lavage culture demonstrating Histoplasma capsulatum. The case represents a unique example of progressive disseminated histoplasmosis in an immunocompetent individual in India.