Open AccessDigital clubbing
Author(s) -
Malay Sarkar,
D M Mahesh,
Irappa Madabhavi
Publication year - 2012
Publication title -
lung india
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 25
eISSN - 0974-598X
pISSN - 0970-2113
DOI - 10.4103/0970-2113.102824
Subject(s) - medicine , asymptomatic , pathogenesis , causation , dermatology , disease , pathology , bioinformatics , political science , law , biology
Digital clubbing is an ancient and important clinical signs in medicine. Although clubbed fingers are mostly asymptomatic, it often predicts the presence of some dreaded underlying diseases. Its exact pathogenesis is not known, but platelet-derived growth factor and vascular endothelial growth factor are recently incriminated in its causation. The association of digital clubbing with various disease processes and its clinical implications are discussed in this review.