Open AccessLower urinary tract symptoms and prostatic calculi: A rare presentation of alkaptonuria
Author(s) -
Francis K Sridhar,
Rajiv Paul Mukha,
Santosh Kumar,
Nitin S Kekre
Publication year - 2012
Publication title -
indian journal of urology/indian journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.333
H-Index - 30
eISSN - 1998-3824
pISSN - 0970-1591
DOI - 10.4103/0970-1591.98474
Subject(s) - alkaptonuria , homogentisic acid , medicine , urinary system , lower urinary tract symptoms , presentation (obstetrics) , ochronosis , urine , urology , dermatology , gastroenterology , surgery , prostate , biochemistry , chemistry , cancer
Alkaptonuria is a rare tyrosine metabolic disorder. A deficiency of homogentisic acid oxidase leads to accumulation of homogentisic acid in the body. Dark-colored urine, cutaneous pigmentations and musculoskeletal deformities are characteristic features. Storage and voiding lower urinary tract symptoms due to prostatic calculi is a rare presentation.