Open AccessPost-transplant small cell carcinoma arising in the native kidney of renal transplant recipient
Author(s) -
Wenhao Tang,
Lulin Ma,
Xiaofei Huang,
Longtao Yan,
Amit Mani Upadhyay
Publication year - 2009
Publication title -
indian journal of urology/indian journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.333
H-Index - 30
eISSN - 1998-3824
pISSN - 0970-1591
DOI - 10.4103/0970-1591.52941
Subject(s) - medicine , kidney , gemcitabine , kidney transplant , kidney transplantation , urology , transplantation , renal cell carcinoma , cisplatin , adjuvant chemotherapy , adjuvant , chemotherapy , surgery , cancer , breast cancer
Small cell carcinoma (SCC) originating from kidney is extremely rare. To date, there has been no reported case of primary SCC of renal transplant recipients' (RTRs)' own kidney. Here, we report the first case of primary SCC of RTRs' own kidney. Resection of bilateral native kidneys, possessing whole length of ureters and small cuffs of bladder along with a neoplasm located in her right kidney, was performed on a 68-year-old female patient, five years after renal transplantation. The immuno-histochemical result confirmed mixed SCC of the right kidney (SCC combined with little transitional cell carcinoma). Postoperatively, platinum-based adjuvant chemotherapy (Cisplatin combined with Gemcitabine) was given, and the patient is still alive with well-functioning transplanted kidney.