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The nested variant of urothelial carcinoma arising in a fibroepithelial polyp: Report of a case and review of literature
Author(s) -
Nadira Mamoon,
Zujajah Hameed,
Fazal Ilahi,
Imran Ahmad
Publication year - 2014
Publication title -
indian journal of urology/indian journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.333
H-Index - 30
eISSN - 1998-3824
pISSN - 0970-1591
DOI - 10.4103/0970-1591.124217
Subject(s) - fibroepithelial polyp , medicine , urothelial carcinoma , stromal cell , pathology , lesion , population , urology , bladder cancer , cancer , ureter , environmental health
The nested variant of urothelial carcinoma is a rare but very important histological entity due to its deceptively bland-looking appearance and aggressive behavior. We present a case of a 30-year-old man who was found to have a solitary polypoid growth in the bladder. It was resected and found to be a fibroepithelial polyp; a rare entity in itself, harboring the above tumor. The lesion also showed a second population of scattered bizarre stromal cells. To our knowledge, this is the first instance of a nested variant of urothelial carcinoma arising in a fibroepithelial polyp. The presence of atypical stromal cells has also not been described previously.

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