Open AccessAsp299Gly and Thr399Ile polymorphism of TLR-4 gene in patients with prostate cancer from North India
Author(s) -
Anjali Priyadarshini,
Anuradha Chakraborti,
Arup Kumar Mandal,
Shrawan Kumar Singh
Publication year - 2013
Publication title -
indian journal of urology/indian journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.333
H-Index - 30
eISSN - 1998-3824
pISSN - 0970-1591
DOI - 10.4103/0970-1591.109982
Subject(s) - genotype , single nucleotide polymorphism , snp , medicine , prostate cancer , genetic predisposition , immune system , gene , etiology , population , polymorphism (computer science) , restriction fragment length polymorphism , gastroenterology , immunology , genetics , cancer , biology , disease , environmental health
The etiological factors associated with prostate cancer (CaP) have not been completely understood as yet. Genetic predisposition and inflammation is fast emerging as risk factors for CaP is a key player in the innate immune response and plays role in immune- surveillance and inflammation. The present study was conducted to evaluate TLR-4 gene polymorphism in patients with CaP.