Open AccessTranscatheter Arterial Chemoembolization Combined with Simultaneous Computed Tomography-guided Radiofrequency Ablation for Large Hepatocellular Carcinomas
Author(s) -
Tai-Yang Zuo,
Fengyong Liu,
Maoqiang Wang,
Xianxian Chen
Publication year - 2017
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.4103/0366-6999.218002
Subject(s) - medicine , radiofrequency ablation , hepatocellular carcinoma , transcatheter arterial chemoembolization , lipiodol , aspartate transaminase , stage (stratigraphy) , radiology , alanine transaminase , survival rate , gastroenterology , ablation , alkaline phosphatase , paleontology , biochemistry , chemistry , biology , enzyme
Currently, the treatment of large hepatocellular carcinoma (HCC) is still a challenging problem. Transcatheter arterial chemoembolization (TACE) is the main treatment for intermediate end-stage HCC, while it is only a palliative and not a curative treatment due to the existence of residual tumors, and radiofrequency ablation (RFA) has limitations in complete ablation of large HCC. We hypothesized that TACE combined with simultaneous RFA (herein referred to as TACE + RFA) could improve the efficacy and survival of large HCC. This study aimed to investigate the feasibility, efficacy, and safety of TACE + RFA on single large HCC.