Open AccessEpigallocatechin-3-gallate Modulates MicroRNA Expression Profiles in Human Nasopharyngeal Carcinoma CNE2 Cells
Author(s) -
Binbin Li,
Guoliang Huang,
Huahui Li,
Xiaoni Kong,
Zhiwei He
Publication year - 2017
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.4103/0366-6999.196586
Subject(s) - nasopharyngeal carcinoma , microrna , gallate , cancer research , gene expression , biology , carcinoma , medicine , oncology , gene , pathology , genetics , pharmacology , radiation therapy
Epigallocatechin-3-gallate (EGCG) has exhibited antitumor properties in several types of cancers, including nasopharyngeal carcinoma (NPC), but the molecular mechanisms underlying this function remain incompletely understood. The aim of the present study was to characterize the global impact of EGCG on the expression of microRNAs (miRNAs) in NPC cells.