Open AccessEvaluation of Basal Serum Adrenocorticotropic Hormone and Cortisol Levels and Their Relationship with Nonalcoholic Fatty Liver Disease in Male Patients with Idiopathic Hypogonadotropic Hypogonadism
Author(s) -
Wenbo Wang,
Fei She,
Lifang Xie,
Wenhua Yan,
Jinzhi Ouyang,
Baoan Wang,
Hongyu Ma,
Li Zang,
Yiming Mu
Publication year - 2016
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.4103/0366-6999.181967
Subject(s) - medicine , endocrinology , hypogonadotropic hypogonadism , adrenocorticotropic hormone , basal (medicine) , dehydroepiandrosterone sulfate , luteinizing hormone , testosterone (patch) , nonalcoholic fatty liver disease , hormone , fatty liver , androgen , disease , insulin
Prolonged gonadal hormone deficiency in patients with idiopathic hypogonadotropic hypogonadism (IHH) may produce adverse effects on the endocrine homeostasis and metabolism. This study aimed to compare basal serum adrenocorticotropic hormone (ACTH) and cortisol levels between male IHH patients and healthy controls. Moreover, this study compared the basal hypothalamic-pituitary-adrenal (HPA) axis in patients with and without nonalcoholic fatty liver disease (NAFLD), and also evaluated the relationship between basal HPA axis and NAFLD in male IHH patients.