Open AccessRenoprotective Effect of the Combination of Renin-angiotensin System Inhibitor and Calcium Channel Blocker in Patients with Hypertension and Chronic Kidney Disease
Author(s) -
Rong Huang,
Yisong Cheng,
Xiao Zeng,
Sehee Kim,
Ping Fu
Publication year - 2016
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.4103/0366-6999.176987
Subject(s) - medicine , calcium channel blocker , blood pressure , renal function , kidney disease , proteinuria , adverse effect , confidence interval , ace inhibitor , urology , angiotensin converting enzyme , kidney
Renin-angiotensin system inhibitor and calcium channel blocker (CCB) are widely used in controlling blood pressure (BP) in patients with chronic kidney disease (CKD). We carried out a meta-analysis to compare the renoprotective effect of the combination of angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) and CCB (i.e., ACEI/ARB + CCB) with ACEI/ARB monotherapy in patients with hypertension and CKD.