Open AccessThymosin Beta-4 Recombinant Adeno-associated Virus Enhances Human Nucleus Pulposus Cell Proliferation and Reduces Cell Apoptosis and Senescence
Author(s) -
Yuanyi Wang,
Qiang Zhu,
Yiwei Wang,
Ruofeng Yin
Publication year - 2015
Publication title -
chinese medical journal/chinese medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 63
eISSN - 2542-5641
pISSN - 0366-6999
DOI - 10.4103/0366-6999.157686
Subject(s) - apoptosis , senescence , recombinant dna , microbiology and biotechnology , cell , cell growth , virology , nucleus , virus , biology , chemistry , cancer research , biochemistry , gene
Thymosin beta-4 (TB-4) is considered key roles in tissue development, maintenance and pathological processes. The study aimed to prove TB-4 positive biological function on nucleus pulposus (NP) cell apoptosis and slowing the process of cell aging while increasing the cell proliferation.