Open AccessIntralesional bleomycin for the treatment of periocular capillary hemangiomas
Author(s) -
Derrick P. Smit,
David Meyer
Publication year - 2012
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/0301-4738.98722
Subject(s) - medicine , debulking , capillary hemangioma , clearance , surgery , cryotherapy , refractory (planetary science) , treatment modality , hemangioma , dermatology , physics , ovarian cancer , cancer , astrobiology , urology
Periocular infantile capillary hemangiomas do not always respond well to conventional treatment modalities such as systemic or intralesional corticosteroids, radiotherapy or debulking surgery. The authors describe the use of intralesional bleomycin injections (IBIs) to treat potentially amblyogenic lesions in two cases where other modalities have failed. In both cases monthly IBIs successfully cleared the visual axis of the affected eye before the age of 1 year thus preventing permanent sensory deprivation amblyopia. A total of five and nine injections, respectively, were used and no significant side effects were noted. IBI appears to be a useful alternative in the treatment of periocular capillary hemangiomas refractory to more conventional modalities.