Open AccessCyclooxygenase-2 expression in primary and recurrent pterygium
Author(s) -
Nermin Karahan,
Şirin Başpınar,
Metin Çiriş,
Çetin Lütfi Baydar,
Nilgün Kapucuoğlu
Publication year - 2008
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/0301-4738.39663
Subject(s) - medicine , pterygium , cyclooxygenase , primary (astronomy) , expression (computer science) , ophthalmology , enzyme , biochemistry , chemistry , physics , astronomy , computer science , programming language
Pterygia are common, benign, fibrovascular, and infiltrative processes of the corneo-conjunctival junction of unknown pathogenesis. Cyclooxygenase-2 (COX-2) mediates the rate-limiting step in arachidonic acid metabolism. Extensive evidence indicates that the COX-2 prostanoid pathway is involved in inflammation. The aim of the study was to document the immunohistochemical expression of COX-2 in primary and recurrent pterygia.