Open AccessEffect of thiamine pyrophosphate on retinopathy induced by hyperglycemia in rats: A biochemical and pathological evaluation
Author(s) -
Emine Çinici,
Ibrahim Ahiskali,
Nihal Cetin,
Bahadır Süleyman,
Osman Kukula,
Durdu Altuner,
Abdülkadir Çoban,
Hilal Balta,
Mehmet Kuzucu,
Halis Süleyman
Publication year - 2016
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/0301-4738.187666
Subject(s) - medicine , thiamine pyrophosphate , glutathione , malondialdehyde , retinopathy , diabetes mellitus , glutathione reductase , endocrinology , edema , diabetic retinopathy , superoxide dismutase , pharmacology , glutathione peroxidase , oxidative stress , biochemistry , enzyme , chemistry , cofactor
Information is lacking on the protective effects of thiamine pyrophosphate (TPP) against hyperglycemia-induced retinopathy in rats. This study investigated the biochemical and histopathological aspects of the effect of TPP on hyperglycemia-induced retinopathy induced by alloxan in rats.