Open AccessCarboplatin loaded polymethylmethacrylate nano-particles in an adjunctive role in retinoblastoma: An animal trial
Author(s) -
Debraj Shome,
Dhrubajyoti Kalita,
Aakanksha Jain,
Rajiv Sarin,
Girish B. Maru,
Jayesh Bellare
Publication year - 2014
Publication title -
indian journal of ophthalmology/indian journal of ophthalmology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 51
eISSN - 1998-3689
pISSN - 0301-4738
DOI - 10.4103/0301-4738.129792
Subject(s) - medicine , carboplatin , retinoblastoma , nano , clinical trial , surgery , chemotherapy , composite material , cisplatin , biochemistry , chemistry , gene , materials science
The purpose of the study is to compare the intra-vitreal concentrations of carboplatin, post peri-ocular injections of commercially available carboplatin (CAC) and a novel carboplatin loaded polymethylmethacrylate nanoparticulate carboplatin (NPC), in either eye, as a model system for treatment of advanced intra-ocular retinoblastoma (RB).