Open Accessp16 immunostaining as a predictor of anal and cervical dysplasia in women attending a sexually transmitted infection clinic
Author(s) -
Deepika Pandhi,
Kavita Bisherwal,
Archana Singal,
Kiran Guleria,
Kiran Mishra
Publication year - 2016
Publication title -
indian journal of sexually transmitted diseases
Language(s) - English
Resource type - Journals
eISSN - 1998-3816
pISSN - 0253-7184
DOI - 10.4103/0253-7184.192125
Subject(s) - medicine , dysplasia , immunostaining , malignancy , carcinogenesis , human papillomavirus , gynecology , cytology , surrogate endpoint , hpv infection , gastroenterology , oncology , pathology , immunohistochemistry , cervical cancer , cancer
Carcinogenesis caused by human papillomavirus (HPV) leads to over-expression of p16 protein. p16 may act as a marker of HPV integration with host genome and serve as a surrogate marker of HPV oncogenesis.