Open AccessA rare case of verrucous carcinoma of penis in an human immunodeficiency virus- infected patient
Author(s) -
Tonita Mariola Noronha,
Banavasi Shanmukha Girisha,
Shubha P. Bhat,
Carol M Christy,
H Sripathi,
Michelle Serene Fernandes
Publication year - 2015
Publication title -
indian journal of sexually transmitted diseases
Language(s) - English
Resource type - Journals
eISSN - 1998-3816
pISSN - 0253-7184
DOI - 10.4103/0253-7184.167174
Subject(s) - verrucous carcinoma , medicine , penis , penile cancer , glans penis , human immunodeficiency virus (hiv) , biopsy , glans , dermatology , amputation , dorsum , cancer , carcinoma , pathology , virology , surgery , anatomy
Cancer is a significant cause of morbidity and mortality in human immunodeficiency virus-infected subjects. Verrucous carcinoma is a peculiarly slow evolving, but relentlessly expanding variant of epidermoid carcinoma that is extremely reluctant to metastasize. A 60-year-old unmarried male patient presented with urethral discharge of 3 weeks duration. Dorsal slit of the prepuce revealed an ulceroproliferative growth measuring 3 cm × 3 cm arising from prepuce and involving glans. Biopsy from the growth in the prepuce showed histopathological features of verrucous carcinoma. Partial amputation of the penis was done. Human papillomavirus DNA by polymerase chain reaction was negative. The patient was started on antiretroviral therapy.