Open AccessEvaluation of the usefulness of Treponema pallidum hemagglutination test in the diagnosis of syphilis in weak reactive Venereal Disease Research Laboratory sera
Author(s) -
Manju Bala,
Aman Toor,
Meenakshi Malhotra,
Monika Kakran,
Sumathi Muralidhar,
V. Ramesh
Publication year - 2012
Publication title -
indian journal of sexually transmitted diseases
Language(s) - English
Resource type - Journals
eISSN - 1998-3816
pISSN - 0253-7184
DOI - 10.4103/0253-7184.102117
Subject(s) - treponema , syphilis , medicine , hemagglutination , disease , virology , test (biology) , sexually transmitted disease , treponematosis , immunology , pathology , biology , virus , human immunodeficiency virus (hiv) , paleontology
Biological false positive (BFP) reactivity by the Venereal Disease Research Laboratory (VDRL) test used for diagnosis of syphilis is a cause for concern. The use of the VDRL as a screening procedure is challenged by some studies. The aim of this study is to determine the prevalence of BFP reactions in different subject groups and to assess the usefulness of Treponema pallidum hemagglutination (TPHA) test in low titre VDRL reactive sera.