Open AccessAssociation of Lyme Disease and Schizoaffective Disorder, Bipolar Type: Is it Inflammation Mediated?
Author(s) -
David William Mattingley,
Maju Mathew Koola
Publication year - 2015
Publication title -
indian journal of psychological medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.417
H-Index - 24
eISSN - 0975-1564
pISSN - 0253-7176
DOI - 10.4103/0253-7176.155660
Subject(s) - schizoaffective disorder , bipolar disorder , schizophrenia (object oriented programming) , mood , psychiatry , bipolar i disorder , medicine , psychosis , lyme disease , disease , psychology , mania , immunology
Lyme disease has been reported to be associated with various psychiatric presentations. Borreliaburgdorferi (Bb) can present with symptoms similar to schizophrenia and bipolar disorder. It has been suggested that inflammation incurred during the Bb infection leads to neurodegenerative changes that result in schizophrenia-like presentations. We report a case of a 41-year-old male with a past history of Bb infection who presents with psychosis. Later in the course of his hospitalization, he developed mood symptoms and was diagnosed with schizoaffective disorder, bipolar type. This case highlights the diagnosis and treatment of a patient with the unique presentation of schizoaffective disorder, bipolar type in the setting of previous Bb infection.