Open AccessA meta-analysis and systematic review of the prevalence of mitochondrially encoded 12S RNA in the general population: Is there a role for screening neonates requiring aminoglycosides?
Author(s) -
Titus S Ibekwe,
Sanjiv Kumar Bhimrao,
Brian D. Westerberg,
Frederick K. Kozak
Publication year - 2015
Publication title -
african journal of paediatric surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.163
H-Index - 17
eISSN - 0189-6725
pISSN - 0974-5998
DOI - 10.4103/0189-6725.160342
Subject(s) - medicine , cochrane library , meta analysis , medline , population , mutation , pediatrics , genetic testing , genetics , family medicine , gene , biology , environmental health , biochemistry
This was a meta-analysis and systematic review to determine the global prevalence of the mitochondrially encoded 12S RNA (MT-RNR1) genetic mutation in order to assess the need for neonatal screening prior to aminoglycoside therapy.