Open AccessHigh tumor volume and local recurrence following surgery in osteosarcoma: A retrospective study
Author(s) -
Rishi Ram Poudel,
Venkatesan Sampath Kumar,
Sameer Bakhshi,
Shivanand Gamanagatti,
Shishir Rastogi,
Shah Alam Khan
Publication year - 2014
Publication title -
indian journal of orthopaedics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.434
H-Index - 33
eISSN - 1998-3727
pISSN - 0019-5413
DOI - 10.4103/0019-5413.132520
Subject(s) - medicine , osteosarcoma , orthopedic surgery , neurovascular bundle , surgery , medical record , outpatient clinic , retrospective cohort study , biopsy , radiology , pathology
Osteosarcoma is a high grade malignant, osteoid forming, primary bone tumor affecting the metaphysis of long bones. Local recurrence (LR) in osteosarcomas is a sinister. Theoretically, a high tumor volume at the time of presentation will limit surgical margins, involve vital neurovascular bundles and show poor response to chemotherapy thereby causing high rates of amputations (as against limb salvage surgery) and should be associated with poor survival rates. This study evaluated objectively if high tumor volume is a significant predictor of local recurrence (LR) in operated cases of osteosarcomas.