
Effect of pre-operative rectal diclofenac suppository on post-operative analgesic requirement in cleft palate repair: A randomised clinical trial
Author(s) -
ES Adarsh,
Rajesh Mane,
CS Sanikop,
SM Iftekhar Uddeen Sagar
Publication year - 2012
Publication title -
indian journal of anaesthesia/indian journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.645
H-Index - 30
eISSN - 0976-2817
pISSN - 0019-5049
DOI - 10.4103/0019-5049.98774
Subject(s) - medicine , diclofenac , suppository , analgesic , anesthesia , nausea , fentanyl , vomiting , sedation , randomized controlled trial , opioid , perioperative , clinical trial , surgery , pharmacology , receptor
Opioid analgesics used for analgesia are associated with sedation, respiratory depression and post-operative nausea and vomiting. Non-steroidal anti-inflammatory drugs such as diclofenac are a safe and effective alternative with opioid-sparing effect.