Open AccessRole of melatonin in attenuation of haemodynamic responses to laryngoscopy and intubation
Author(s) -
Priyamvada Gupta,
Durga Jethava,
Ruchika Choudhary,
Dharam Das Jethava
Publication year - 2016
Publication title -
indian journal of anaesthesia/indian journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.645
H-Index - 30
eISSN - 0976-2817
pISSN - 0019-5049
DOI - 10.4103/0019-5049.191667
Subject(s) - medicine , laryngoscopy , intubation , melatonin , hemodynamics , anesthesia
Laryngoscopy and endotracheal intubation are considered as potent stimuli which lead to an increase in heart rate and blood pressure. Melatonin ( N -acetyl-5-methoxytryptamine) has been studied for pre-operative anxiolysis and sedation in Intensive Care Unit. We made a hypothesis that melatonin can provide haemodynamic stability during laryngoscopy and intubation when given 120 min before the procedure.