Open AccessReversal agents in anaesthesia and critical care
Author(s) -
Nibedita Pani,
Pradeep A Dongare,
Rajeeb Kumar Mishra
Publication year - 2015
Publication title -
indian journal of anaesthesia/indian journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.645
H-Index - 30
eISSN - 0976-2817
pISSN - 0019-5049
DOI - 10.4103/0019-5049.167484
Subject(s) - sugammadex , rocuronium , medicine , neuromuscular blockade , rapid sequence induction , neuromuscular blocking agents , anesthesia , intensive care medicine , drug , pharmacology , propofol , intubation
Despite the advent of short and ultra-short acting drugs, an in-depth knowledge of the reversal agents used is a necessity for any anaesthesiologist. Reversal agents are defined as any drug used to reverse the effects of anaesthetics, narcotics or potentially toxic agents. The controversy on the routine reversal of neuromuscular blockade still exists. The advent of newer reversal agents like sugammadex have made the use of steroidal neuromuscular blockers like rocuronium feasible in rapid sequence induction situations. We made a review of the older reversal agents and those still under investigation for drugs that are regularly used in our anaesthesia practice.