Open AccessEmphysematous pancreatitis predisposed by Olanzapine
Author(s) -
Sukhen Samanta,
Sujay Samanta,
Krishanu Banik,
Arvind Kumar Baronia
Publication year - 2014
Publication title -
indian journal of anaesthesia/indian journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.645
H-Index - 30
eISSN - 0976-2817
pISSN - 0019-5049
DOI - 10.4103/0019-5049.135049
Subject(s) - medicine , acute pancreatitis , olanzapine , pancreatitis , diabetes mellitus , hypertriglyceridemia , intensive care unit , gastroenterology , immunosuppression , pancreas , surgery , triglyceride , endocrinology , schizophrenia (object oriented programming) , psychiatry , cholesterol
A 32-year-old male presented to our intensive care unit with severe abdominal pain and was diagnosed as acute pancreatitis after 2 months of olanzapine therapy for bipolar disorder. His serum lipase was 900 u/L, serum triglyceride 560 mg/dL, and blood sugar, fasting and postprandial were 230 and 478 mg/dL, respectively on admission. Contrast enhanced computed tomography (CECT) of abdomen was suggestive of acute pancreatitis. Repeat CECT showed gas inside pancreas and collection in peripancreatic area and patient underwent percutaneous drainage and antibiotics irrigation through the drain into pancreas. We describe the rare case of emphysematous pancreatitis due to development of diabetes, hypertriglyceridemia and immunosuppression predisposed by short duration olanzapine therapy.