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() is a round-shaped Gram-positive bacteria that caused infection in the human body.  infection can be inhibited by the use of antibiotics. However, these bacteria displayed resistance to some antibiotics. The purpose of this study is to determine the effects of Tembelekan (.) and Kopasanda () leaf extracts against . The method used in this study is the disc method to determine the inhibition zone. The test results showed there was no significant difference in the sensitivity of Tembelekan leaf extract () and Kopasanda leaf extract () against  (P0.8>α0.05). However, based on the average value of the inhibition zone, Kopasanda leaf extract was showed higher inhibition zone compared to Tembelekan leaf extract. In conclusion, Tembelekan leaf and Kopasanda leaf at a concentration of 100% were produced inhibition zones of 0.6 cm and 0.8 cm respectively against

The Antibacterial Activity of Tembelekan Leaf (Lantana camara L.) and Kopasanda Leaf (Chromolaena odorata L.) Extracts against Staphylococcus aureus